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Research Grants

beakers.svgWe’re proud to offer grant opportunities that provide funding to physicians and scientists in the field of Primary Immunodeficiency. These efforts help researchers advance science and save lives.

In this section, you’ll find information about how to be considered for the following grants: the Translational Research Program, the Specific Defect Research Program, and C.H.I.L.D.R.E.N! (Child Health Initiative to Lessen Disease through Research and Education Now).

Translational Research Program

stethescope.svgPrimary Immunodeficiencies occur when components of the immune system are missing or do not function properly, causing hyper-susceptibility to infection and in some cases severe autoimmunity, IBD, and respiratory diseases. Over the past decade, identification and diagnosis of Primary Immunodeficiency has greatly expanded, and knowledge of causative genes continues to rapidly grow. To date, there are over 450 specific genetic defects identified, which has not only helped advance new therapies but has also been instrumental in advancing our understanding of immunology. It is estimated that as many as 10 million people, if not more, are living with Primary Immunodeficiency worldwide. As such, the time is crucial to support research that will bridge basic science discoveries to the development of clinical applications that will impact overall health outcomes. Advancing research that enhances our understanding of the immune system represents one of the single greatest strategies that biomedical science has to offer to identify new therapies and will greatly benefit those with Primary Immunodeficiencies and the millions that remain undiagnosed.

Purpose

  • To support innovative and novel investigations in Primary Immunodeficiency, focusing on translational research leading to meaningful clinical application.
  • To advance the growing knowledge of genotype-phenotype correlations and gain a better understanding of the underlying mechanisms of immune function and dysfunction.
  • To support research that will lead to advancement in clinical recognition, diagnostic tools, and innovative therapies that will impact overall health outcomes and improve the quality of life of those affected by Primary Immunodeficiency.
  • Grants with the following focus will be strongly considered for awards:
  • Novel Primary Immunodeficiency defects
  • Innovative approaches to early diagnosis -Novel therapeutic strategies
  • Translational impact on patient health (i.e. how a patient will benefit)
  • Reach of the proposed project (i.e. how many patients might benefit)
  • Projects that currently do not have funding and would be otherwise difficult to advance without this award

Eligibility

The Jeffrey Modell Foundation encourages all investigators with the appropriate knowledge and research skill level to apply to this program. Applications submitted by investigators with vast expertise in Primary Immunodeficiency, as well as young investigators with robust scientific merit will all be considered. All international and U.S. applicants are eligible. JMF especially encourages investigators who are not currently receiving funding from the National Institutes of Health to apply. Only one active grant at a time per investigator is permitted.

Review Process

All applications will be comprehensively reviewed and evaluated by the Jeffrey Modell Centers Network Peer Review Research Committee. The committee will provide an impact score for individual applications based on:

  • Innovativeness
  • Originality
  • Feasibility
  • Justification of requested budget
  • Translational applicability
  • Relevance to Primary Immunodeficiency
  • Relevance to advancement of the work

Award Information

The number of awards will be dependent on the strength and merit of applications received and on the availability of funds. Individual awards may total up to $250,000 over a two-year project period. Funds are not to exceed $125,000 per year for each project. Total funds will support only direct costs and cannot be used for institutional overhead. JMF reserves the right to reduce the award amount for any application.

Application Timeline

To date, a total of 16 grants have been awarded throughout 9 cycles. The 10th cycle will begin on January 17, 2022. A Letter of Intent must be submitted by March 14, 2022, and invited investigators must submit full applications by July 5th, 2022 to be considered for the 10th cycle of awards. Grants will be awarded by November 18, 2022. 

Application Deadline

Start Date - January 17, 2022
Letter of Intent Deadline - March 14, 2022
Application Deadline - July 5, 2022
Grant Awards - November 18, 2022

Required Application Materials: Note: Application materials must meet the requirements below. Any applications that exceed the page limits will not be considered.

Letter of Intent

A Letter of Intent (LOI) must be submitted by March 14th, 2022, separate from and prior to the full application. Investigators who have submitted an LOI and have been invited by the JMCN Research Committee to submit a full grant application will be considered for funding. Please download and complete the LOI form at this link, which provides additional instructions.

Application

Please download and complete the application.

Research Proposal

Please attach a detailed research proposal outlining the specific aims, background, purpose, and goals of the intended project. This proposal should be approximately 6 pages. Tables, figures, and graphs, etc. may also be included as supplemental documentation to support the 6-page proposal. For application re-submission, please include an updated revision statement. Only one application re-submission is permitted.

Budget and Budget Justification

A budget and detailed budget justification must be attached with the application. The budget justification should not exceed 2 pages. Curriculum Vitae/Biosketch Please attach your most current curriculum vitae or biosketch, highlighting experience as it relates to your proposed project. Please also list publications in order of relevance to the proposal. Please try to limit your CV or Biosketch to no more than 5 pages.

Application Submission and Inquiries

The Jeffrey Modell Foundation encourages submission of the application and all required materials to research@jmfworld.org. Applicants who prefer to submit a paper-based application may send all materials to the following address or by fax:

Jeffrey Modell Foundation 
780 Third Avenue, 47th Floor 
New York, NY 10017 
Fax: 212-764-4180

All inquiries and logistical questions should be submitted to the Jeffrey Modell Foundation Program Officer at research@jmfworld.org.

Specific Defect Research Program

stethescope.svg The goal of the Specific Defect Research Program is to support research to study the mechanisms and presentation of specific defects of the immune system, leading to a better understanding of the conditions and their impact on overall health outcomes. The Jeffrey Modell Foundation database includes high numbers of various genotypes around the world. This database can provide an excellent platform for collaboration. This can evolve into sharing patient samples and setting up international collaborative studies. Working together with the Jeffrey Modell Foundation, investigators will have access to this international database and be able to contact other sites in order to coordinate studies.

Award Information

Currently, there are 36 Specific Defect Research Grants in progress. These include:

  1. ARTEMIS
  2. Autoimmune Cytopenias
  3. CARD11
  4. CARD9/CMC
  5. Chronic Mucocutaneous Candidiasis Disease
  6. Common Variable Immunodeficiency
  7. Complete DiGeorge Syndrome
  8. Congenital Agammaglobulinemia
  9. Early Onset Autoimmune Cytopenia
  10. FOXP3/IPEX
  11. FOXP3/Regulatory T cells fulminant viral hepatitis
  12. IL10 Receptor Deficiency
  13. IPEX/IPEX like syndromes
  14. IRF2BP2
  15. LRBA Deficiency
  16. MHC Polymorphisms in CVID
  17. NEMO
  18. Opportunistic Infections
  19. Post-HSCT Idiopathic Pneumonia
  20. RAG1/RAG2 deficiencies
  21. SNP's in MHC
  22. STAT3
  23. Streptococcus Pneumonia​ ​in CVID
  24. VEO-IBD
  25. WES to identify new genetic phenotypes
  26. WGS to identify pathogenic gene mutations underlying PI
  27. WHIM
  28. Whole Genome Sequencing
  29. X-Linked CGD
  30. X-Linked Hyper IgM syndrome
  31. XLA
  32. XMEN
  33. Zap70 deficiency

The Jeffrey Modell Foundation encourages novel investigations to expand upon this list of Specific Defect Research Grants.

Awards are granted on a rolling basis throughout the year. Each award amounts up to $50,000 over a two-year project period, with a maximum of $25,000 per year.

Required Application Materials

Application

Please download and complete the application.

Research Proposal

Please attach a detailed research proposal outlining the specific aims, background, purpose, and goals of the intended project. This proposal should be approximately 3-4 pages. Tables, figures, and graphs, etc. may also be included as supplemental documentation to support the proposal.

Budget and Budget Justification

A budget and detailed budget justification must be attached with the application. The budget justification should not exceed 2 pages.

Curriculum Vitae/Biosketch

Please attach your most current curriculum vitae or biosketch, highlighting experience as it relates to your proposed project. Please also list publications in order of relevance to the proposal.

Application Submission and Inquiries

Applications for this program are currently accepted and reviewed on a rolling basis, so you may apply at any time. JMF encourages submission of the application and all required materials by email at research@jmfworld.org. Applicants who prefer to submit a paper-based application may send all materials to the following address or by fax:

Jeffrey Modell Foundation 
780 Third Avenue, 47th Floor 
New York, NY 10017 
Fax: 212-764-4180

All inquiries and logistical questions should be submitted to the Jeffrey Modell Foundation Program Officer at research@jmfworld.org.

C.H.I.L.D.R.E.N!®

logo-children.svg

Project Mission

To alleviate disease, seek cures, and ultimately improve the quality of life of children affected with Primary Immunodeficiency throughout the world. The focus of this grant program is to investigate immunological disorders, control of infectious disease, and initiatives to decrease infant mortality. Additionally, the Jeffrey Modell Foundation encourages applicants to strongly consider addressing healthcare disparities, especially in developing countries, through education, testing, diagnosis, and treatment.

Project Objectives

  1. To stimulate research by attracting innovative and public health-focused investigations of Primary Immunodeficiency research.
  2. To support innovative investigations in Primary Immunodeficiency diseases and novel clinical strategies to detect Primary Immunodeficiency diseases, and to develop innovative new therapies.
  3. To apply cellular, genomic, and molecular biological principles to Primary Immunodeficiency research; to create new platforms for diagnostics including genome and exome sequencing.
  4. To focus on immunological disorders, control of infectious disease, and infant mortality, especially in developing countries; to seek and promote safe, effective, and appropriate vaccines.
  5. To address healthcare disparities, especially in developing countries, through education, testing, diagnosis, and treatment.
  6. To build upon the Jeffrey Modell Foundation’s existing platforms of critical technology including the TREC and KREC assays for Newborn Screening; to develop laboratory diagnostics or build partnerships with institutions that have existing laboratory diagnostics.
  7. To maximize collaboration through integration with the Jeffrey Modell Centers Network and to replicate successful programs achieved at leading academic medical centers with application to global health; to build partnerships throughout the Network through fellowships, training, symposia, and other continuing medical education–focused initiatives.

Funding Availability

Up to $25,000 per year, for up to 2 years, for each grant awarded through the C.H.I.L.D.R.E.N! project that is peer-reviewed and approved.

Required Application Materials

Application

Please download and complete the application.

Research Proposal

Please attach a detailed research proposal outlining the specific aims, background, purpose, and goals of the intended project. This proposal should be approximately 3-4 pages. Tables, figures, and graphs, etc. may also be included as supplemental documentation to support the proposal.

Budget and Budget Justification

A budget and detailed budget justification must be attached with the application. The budget justification should not exceed 2 pages.

Curriculum Vitae/Biosketch

Please attach your most current curriculum vitae or biosketch, highlighting experience as it relates to your proposed project. Please also list publications in order of relevance to the proposal.

Application Submission and Inquiries

Applications for this program are currently accepted and reviewed on a rolling basis, so you may apply at any time. JMF encourages submission of the application and all required materials by email at research@jmfworld.org. Applicants who prefer to submit a paper-based application may send all materials to the following address or by fax:

Jeffrey Modell Foundation 
780 Third Avenue, 47th Floor 
New York, NY 10017 
Fax: 212-764-4180

All inquiries and logistical questions should be submitted to the Jeffrey Modell Foundation Program Officer at research@jmfworld.org

Travel Grants

Education is an essential part of what we do at the Jeffrey Modell Foundation. Travel grants are offered to enhance physician and nurse education. Grantees are awarded support to travel to national and international medical conferences that highlight Primary Immunodeficiency, with the hope that they’ll come back richer in their understanding.

WinMD Offers Grants to Physicians Worldwide

WIN-MD.svg

Looking for Primary Immunodeficiency? Find a doctor! WinMD is a program that provides funding to medical students, fellows, researchers, and physicians to support travel to national and international medical conferences that highlight Primary Immunodeficiencies. The goal is to enhance physician education, promote awareness, and to create a lively dialogue with colleagues.

Download the application


WinRN Offers Grants to Nurses Worldwide

WIN-RD.svg

Looking for Primary Immunodeficiency? Find a nurse! WinRN is a program that provides funding to nurses for travel and lodging to national and international medical conferences that highlight Primary Immunodeficiencies. The goal is to enhance education, promote awareness, and to create a lively dialogue with colleagues.

Download the application

Conferences

globe.svgMedical Conferences provide valuable information and experiences to physicians and healthcare professions in our field.

Start Date:
Tue June 18, 2024
End Date:
Fri June 21, 2024
Name:
FOCIS (Federation of Clinical Immunology Societies)
Location:
San Francisco, California
Link:
Start Date:
Wed October 18, 2023
End Date:
Sat October 21, 2023
Name:
LASID (Latin American Society for Immunodeficiencies)
Location:
Mexico City, Mexico
Link:
Start Date:
Tue June 20, 2023
End Date:
Fri June 23, 2023
Name:
FOCIS (Federation of Clinical Immunology Societies)
Location:
Boston, Massachusetts, USA
Link:
Start Date:
Thu May 18, 2023
End Date:
Sun May 21, 2023
Name:
CIS (Clinical Immunology Society)
Location:
St. Louis, Missouri, USA
Link:
Start Date:
Thu May 11, 2023
End Date:
Mon May 15, 2023
Name:
AAI (American Academy of Immunologists)
Location:
Washington, DC, USA
Link:
Start Date:
Fri February 24, 2023
End Date:
Mon February 27, 2023
Name:
AAAAI (American Academy of Allergy, Asthma & Immunology)
Location:
San Antonio, Texas, USA
Link:
Start Date:
Thu November 10, 2022
End Date:
Mon November 14, 2022
Name:
ACAAI (American College of Allergy, Asthma & Immunology)
Location:
Louisville, Kentucky, USA
Link:
Start Date:
Wed October 12, 2022
End Date:
Sat October 15, 2022
Name:
20th Biennial Meeting 2022 ESID (European Society for Immunodeficiencies)
Location:
Gothenburg, Sweden
Link:
Start Date:
Thu September 29, 2022
End Date:
Sun October 2, 2022
Name:
IgNS (Immunoglobulin National Society)
Location:
Washington, DC, USA
Link:
Start Date:
Tue June 21, 2022
End Date:
Fri June 24, 2022
Name:
FOCIS (Federation of Clinical Immunology Societies)
Location:
San Francisco, California, USA
Link:
The Jeffrey Modell Foundation's Medical Academy takes great pride in supporting novel, cutting edge, and innovative research. Here, physicians, scientists, and
  • The Jeffrey Modell Foundation's Medical Academy takes great pride in supporting novel, cutting edge, and innovative research. Here, physicians, scientists, and
  • young investigators have the opportunity to apply for a variety of grants. The research grants are to enhance the quality of life, advance new treatments, and ultimately
  • find cures; the travel grants are to encourage physicians and nurses to attend conferences worldwide. Our Academy lives and breathes opportunity: let’s seize it!