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10 Warning Signs of Primary Immunodeficiency

The Jeffrey Modell Foundation has created the 10 Warning Signs of Primary Immunodeficiency to continue its mission to assure earliest possible diagnosis.

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If you or someone you know is affected by two or more of the following Warning Signs, speak to a physician about the possible presence of an underlying Primary Immunodeficiency.

The 4 Stages of Testing Poster

To assist physicians in making a Primary Immunodeficiency diagnosis.

10 Warning Signs of WHIM

10 Warnings Signs of CGD

10 Warning Signs International

The Jeffrey Modell Foundation has created the 10 Warning Signs of Primary Immunodeficiency to continue its mission to assure earliest possible diagnosis.

Arabic

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Armenian

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Azerbaijani

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Bosnian

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Bulgarian

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Chinese

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Croatian

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Dutch

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English

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Estonian

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Farsi

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Finnish

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French

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German

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Greek

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Hebrew

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Hindi

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Hungarian

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Indonesian

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Italian

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Japanese

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Kazakh

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Korean

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Lithuanian

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Luganda (Uganda, Africa)

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Malay

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Mongolian

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Noni

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Oriya

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Pidgin (Cameroon, Africa)

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Polish

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Portuguese

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Romanian

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Runyakitara (Uganda, Africa)

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Russian

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Serbian

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Slovak

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Slovene

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Spanish

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Swahili

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Swedish

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Turkish

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Ukrainian

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Urdu

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Vietnamese

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Educational Books

In addition to the 10 Warning Signs Posters, we have produced the following educational materials to inform the public about Primary Immunodeficiency.

Funny Immunology To Save Lives!

English

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Spanish

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Portuguese

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Russian

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Arabic

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Immune System Posters

An educational illustration of how our immune system works.

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  • immune-system-dutch-child-resize-274x412-55e862640982b-original.jpg
  • immune-system-dutch-adult-resize-271x411-55e8625e4ed89-original.jpg
  • immune-system-spanish-resize-297x424-54db91594bd83-original.jpg
  • immune-system-polish-resize-409x578-54dbc681991f0-original.jpg
  • immune-system-slovene-resize-373x583-54dbc77be4cf2-original.jpg
  • immune-system-serbian-resize-383x582-54dbc7e8917b1-original.jpg
  • immune-system-german-resize-323x529-54dbbe3469ab4-original.jpg
  • immune-system-kazakh-resize-338x519-54dbbe3ad8571-original.jpg
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Informational Brochures

CGD Accordion Brochure

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A pocket-sized guide to Primary Immunodeficiency

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  • spanish-accordion-cover-2020-resize-826x600-5dfa5c5567368-original.jpg
  • fireman-resize-293x216-5bd9d97aa0dab-original.jpg
  • rockstar-spanish-resize-291x216-5bd9d980cc9ea-original.jpg

A detailed and informative guide to Primary Immunodeficiency.

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As well as in collaboration with our pharmaceutical partners!

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JMF Book - Immunology and Primary Immunodeficiencies

Immunology and Primary Immunodeficiencies

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The Fantastic Interleukins

English

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Spanish

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Why Immunology?

The Importance of the Immune System!

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Physician Education Materials

doctor.svgThe clinical presentation of Primary Immunodeficiency can be diverse. However, there are clinical findings at the level of different organs and systems requiring Primary Immunodeficiency suspicion; these findings must be quickly recognized by specialty care physicians.

La presentación clínica de las Inmunodeficiencias Primarias puede ser muy variada. Sin embargo, existen hallazgos clínicos a nivel de diferentes órganos y sistemas que obligan a sospechar Inmunodeficiencias Primarias; estos hallazgos deben ser rápidamente reconocidos por los médicos especialistas:

Clinical Trial: Do you have Chronic, Congenital, or Cyclical Neutropenia?

A Quick Guide to Activated PI3K Delta Syndrome (APDS)

A Guide for Medical Professionals - Chronic Granulomatous Disorder

  

Diagnostic Algorithm for Specialty Care Physicians

          

OMIM® - Online Mendelian Inheritance in Man®

OMIM® - Online Mendelian Inheritance in Man®


An Online Catalog of Human Genes and Genetic Disorders
OMIM contains information on all known mendelian disorders and over 15,000 genes, with a specific focus on the relationship between phenotype and genotype.

OMIM is authored and edited at the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine.  It is updated daily, and the entries contain copious links to other genetics resources.

Learn more at OMIM.org
 

Interesting Scientific Research

  • The FILL (Following infants with low lymphocytes) study developed as an offshoot and direct result of newborn screening for SCID and T cell lymphopenia (NBS SCID) in the United States.  This study intends to enroll infants who are initially identified during newborn screening (abnormal TREC result on SCID screening) and confirmed by a physician to have lymphopenia.  The study will collect data on 200 infants who are enrolled by April 1, 2018.  The FILL database was created and is maintained by the USIDNET, through a pilot grant provided by the Jeffrey Modell Foundation to the Clinical Immunology Society (CIS).   Patient data can be entered into the FILL Database either by enrollment through an USIDNET center, or through direct physician referral to USIDNET.  All patients enrolled in the study have to be consented through an IRB protocol.

    We strongly urge you to enroll your patients with T cell lymphopenia identified by SCID newborn screening in the FILL study so that there is evidence-based data to better understand, follow and manage infants with lymphopenia.

  • Clinical Trial Opportunity for Patients with Chronic Mucocutaneous Candidiasis
    Chronic Mucocutaneous Candidiasis often results from an underlying immune deficiency that leads to abnormalities in a person’s control of fungal infections such as candida.  Investigators at NIAID are seeking people with chronic mucocutaneous candidiasis (oropharyngeal, esophageal or vulvovaginal candidiasis) that are refractory or intolerant to standard non-intravenous therapies to participate in a clinical research trial.  For additional information please contact Dr. Alexandra Freeman (freemaal@mail.nih.gov) or see https://clinicaltrials.gov/ct2/show/NCT02629419.

  • Monozygotic twins discordant for CVID reveal impaired DNA demethylation during naïve-to-memory B-cell transition

  • 'JEDI' technology awakens new understanding of how immune system works

Clinical Trials, Physician Research Opportunities

  • Ground Breaking News for Patients with LAD-1 deficiency!

Some exciting news just in! Rocket Pharma has disclosed exciting information about their gene therapy trial for patients with LAD-1 deficiency. Please read the summary, which describes the clinical trial, the disease, and the six month data showing the therapy was well tolerated and induced a restoration of CD18 levels.

 

  • X4 Pharmaceuticals planning to start a Phase 3 clinical study: “A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of mavorixafor (X4P-001) in Patients with WHIM Syndrome with Open-Label Extension”

WHIM (Warts, Hypogammaglobulinemia, Infections and Myelokathexis) is a rare autosomal dominant primary immunodeficiency disease caused by gain-of-function mutations in the chemokine receptor CXCR4.  CXCR4 mutations induce increased leukocyte homing and retention in the bone marrow resulting in severe chronic neutropenia and lymphopenia.  

X4 Pharmaceuticals is planning to sponsor a 52-week global Phase 3 study to evaluate the safety and efficacy of mavorixafor, a once-daily oral CXCR4 antagonist, in genetically confirmed WHIM patients who are aged 12 years or older.  Mavorixafor is a first-in-class, oral, small molecule antagonist of the CXCR4 chemokine receptor that has demonstrated a favorable safety profile and dose-dependent increases in ANC and ALC in a Phase 2 study. Trial subjects will participate in a one-year trial with an opportunity to continue in the subsequent open label extension.  Travel support to study sites will be provided. 

To support confirming the diagnosis of WHIM, X4 Pharmaceuticals will offer genetic testing at no charge to patients meeting eligibility criteria suggestive for the disease.  For information and support for genetic confirmation of your patients with suspected WHIM, please contact patientinfo@x4pharma.com.

To learn more about X4 Pharmaceuticals, visit their website, at x4pharma.com

  • The FILL (Following infants with low lymphocytes)

This study developed as an offshoot and direct result of newborn screening for SCID and T cell lymphopenia (NBS SCID) in the United States.  This study intends to enroll infants who are initially identified during newborn screening (abnormal TREC result on SCID screening) and confirmed by a physician to have lymphopenia.  The study will collect data on 200 infants who are enrolled by April 1, 2018. The FILL database was created and is maintained by the USIDNET, through a pilot grant provided by the Jeffrey Modell Foundation to the Clinical Immunology Society (CIS).   Patient data can be entered into the FILL Database either by enrollment through an USIDNET center, or through direct physician referral to USIDNET.  All patients enrolled in the study have to be consented through an IRB protocol.

We strongly urge you to enroll your patients with T cell lymphopenia identified by SCID newborn screening in the FILL study so that there is evidence-based data to better understand, follow and manage infants with lymphopenia.

  • Clinical Trial Opportunity for Patients with Chronic Mucocutaneous Candidiasis

Chronic Mucocutaneous Candidiasis often results from an underlying immune deficiency that leads to abnormalities in a person’s control of fungal infections such as candida.  Investigators at NIAID are seeking people with chronic mucocutaneous candidiasis (oropharyngeal, esophageal or vulvovaginal candidiasis) that are refractory or intolerant to standard non-intravenous therapies to participate in a clinical research trial.  For additional information please contact Dr. Alexandra Freeman (freemaal@mail.nih.gov) or see https://clinicaltrials.gov/ct2/show/NCT02629419.

Funny Immunology To Save Lives!

English

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Spanish

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Portuguese

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Russian

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Arabic

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In the IMMUNEWS

The IMMUNEWS showcases exciting Foundation programs and events, and also focuses on community and industry news.

Choose from one of our issues below:

IMMUNEWS – 2011

IMMUNEWS – 2010

IMMUNEWS – 2009

IMMUNEWS – 2008

IMMUNEWS – 2007

IMMUNEWS – 2006

IMMUNEWS – 2005

IMMUNEWS – 2004

IMMUNEWS – 2003

IMMUNEWS – 2002

IMMUNEWS – 2001

Reading Materials

We want to share stories, experiences, scientific textbooks, and the knowledge of physicians, families, and patient organizations within the Primary Immunodeficiency community.

Scientific Publications

beakers.svgIf you're looking for information on groundbreaking scientific material, you’ll find some of it here. See below for a list of publications about gene discovery, new defects, and more.

Author(s):
Quinn, J., Modell, V., Aradhya S., Johnson B., Orange, J.S., Poll, S., Modell, F.
Name:
Global Expansion of Jeffrey’s Insights: Jeffrey Modell Foundation’s Genetic Sequencing Program for Primary Immunodeficiency
Author(s):
Frontiers in Immunology
Publication Date:
2022 June 10
DOI:
doi: 10.3389/fimmu.2022.906540
Author(s):
Rider N, Miao D, Dodds M, Modell V, Modell F, Quinn J, Schwarzwald H, Orange J.
Name:
Calculation of a Primary Immunodeficiency "Risk Vital Sign" via Population-Wide Analysis of Claims Data to Aid in Clinical Decision Support.
Author(s):
Frontiers in Pediatrics.
Publication Date:
2022 April 16
DOI:
doi: 10.3389/fped.2019.00070
Name:
Global study of primary immunodeficiency diseases (PI) – diagnosis, treatment, and economic impact: an updated report from the Jeffrey Modell Foundation
Author(s):
Springer
Publication Date:
2022 April 16
DOI:
doi: 10.100/s12026-011-8241-y
Name:
The Impact of Physician Education & Public Awareness on Early Diagnosis of Primary Immunodeficiency
Publication Date:
2022 April 16
Name:
From genotype to phenotype. Further studies measuring the impact of a Physician Education and Public Awareness Campaign on early diagnosis and management of Primary Immunodeficiencies
Author(s):
Immunologic Research
Publication Date:
2022 April 16
DOI:
doi: 10.1007/s12026-008-8092-3
Name:
June 2007 IUIS PI Expert Committee Summary Report - Geha RS, et al
Publication Date:
2022 April 16
Name:
Immunology Today and New Discoveries: Building Upon Legacies of Dr. Robert A. Good
Publication Date:
2022 April 16
Name:
Consensus Recommendations for the use of Immunoglobulin Replacement Therapy in Immune Deficiency
Author(s):
APIIEG
Publication Date:
2022 April 16
Name:
Timeline of Discovery, Advances in Treatment, and Scientific Understanding of PI
Publication Date:
2022 April 16
Name:
Council for Harvard Medicine Keynote: December 8, 2005
Publication Date:
2022 April 16
Author(s):
Quinn, J., Modell, V., Orange, J.S., Modell, F.
Name:
Growth in diagnosis and treatment of primary immunodeficiency within the global Jeffrey Modell Centers Network.
Author(s):
Allergy Asthma Clin Immunol.
Publication Date:
2022 March 22
DOI:
doi: 10.1186/s13223-022-00662-6
Author(s):
Quinn J, Modell V, Holle J, Truty R, Aradhya S, Johnson B, Orange J, Modell F.
Name:
Jeffrey’s insights: Jeffrey Modell Foundation’s global genetic sequencing pilot program to identify specific primary immunodeficiency defects to optimize disease management and treatment.
Author(s):
Immunologic Res.
Publication Date:
2020 May 27
DOI:
doi: 0.1007/s12026-020-09131-x
Author(s):
Quinn J, Orange J, Modell V, Modell F.
Name:
The case for severe combined immunodeficiency (SCID) and T cell lymphopenia newborn screening: saving lives…one at a time
Author(s):
Immunologic Res.
Publication Date:
2020 March 4
DOI:
doi: 10.1007/s12026-020-09117-9
Author(s):
Modell V, Orange J, Quinn J, Modell M.
Name:
Global report on primary immunodeficiencies: 2018 update from the Jeffrey Modell Centers Network on disease classification, regional trends, treatment modalities, and physician reported outcomes.
Author(s):
Immunologic Res.
Publication Date:
2018 May 9
DOI:
doi: 10.1007/s12026-018-8996-5
Author(s):
Aghamohammadi A, Abolhassani H, Quinn J, Modell F, Modell V, The JMF Centers Network Investigators and Study Collaborators, et al.
Name:
Patients with Primary immunodeficiencies are a reservoir of Poliovirus and a risk to Polio eradication.
Author(s):
Frontiers in Immunology
Publication Date:
2017 June 1
Author(s):
Modell V, Quinn J, Ginsberg G, Gladue R, Orange J, Modell F.
Name:
Modeling strategy to identify patients with primary immunodeficiency utilizing risk management and outcome measurement.
Author(s):
Immunologic Res.
Publication Date:
2017 February 21
DOI:
doi: 10.1007/s12026-017-8907-1
Author(s):
Modell V, Quinn J, Orange J, Notarangelo LD, Modell F.
Name:
Primary Immunodeficiencies worldwide: an updated overview from the Jeffrey Modell Centers Global Network.
Author(s):
Immunologic Res.
Publication Date:
2016 January 22
DOI:
doi: 10.1007/s12026-016-8784z
Name:
Genetics of SCID
Publication Date:
2015 November 15
Author(s):
Modell V, Knaus M, Modell F, Roifman C, Orange J, Notarangelo LD.
Name:
Global overview of primary immunodeficiencies: a report from Jeffrey Modell Centers worldwide focused on diagnosis, treatment, and discovery.
Author(s):
Immunologic Res.
Publication Date:
2014 March 26
DOI:
doi: 10.1007/s12026-014-8498-z
Author(s):
Modell V, Knaus M, Modell F.
Name:
An analysis and decision tool to measure cost benefit of newborn screening for severe combined immunodeficiency (SCID) and related T-cell lymphopenia.
Author(s):
Immunologic Res.
Publication Date:
2014 March 6
DOI:
doi: 10.1007/s12026-014-8485-4
Author(s):
Shearer WT, Dunn E, Notarangelo LD, Dvorak CC, Puck JM, Logan BR, Griffith LM, Kohn DB, O'Reilly RJ, Fleisher TA, Pai SY, Martinez CA, Buckley RH, Cowan MJ.
Name:
Establishing diagnostic criteria for severe combined immunodeficiency disease (SCID), leaky SCID, and Omenn syndrome: The Primary Immune Deficiency Treatment Consortium experience.
Author(s):
J Allergy Clin Immunol.
Publication Date:
2013 November 27
DOI:
doi: S0091-6749(13)01495-4
Author(s):
Rawat A, Singh S, Suri D, Gupta A, Saikia B, Minz RW, Sehgal S, Vaiphei K, Kamae C, Honma K, Nakagawa N, Imai K, Nonoyama S, Oshima K, Mitsuiki N, Ohara O, Chan KW, Lau YL.
Name:
Chronic granulomatous disease: two decades of experience from a tertiary care centre in north west India.
Author(s):
J Clin Immunol.
Publication Date:
2013 November 26
DOI:
doi: 10.1007/s10875-013-9963-5
PMID:
24276928
Author(s):
Costa-Carvalho BT, Grumach AS, Franco JL, Espinosa-Rosales FJ, Leiva LE, King A, Porras O, Bezrodnik L, Oleastro M, Sorensen RU, Condino-Neto A.
Name:
Attending to Warning Signs of Primary Immunodeficiency Diseases across the range of clinical practice.
Author(s):
J Clin Immunol.
Publication Date:
2013 November 16
DOI:
doi: 10.1007/s10875-013-9954-6
PMID:
24241582
PMCID:
PMC3930833
Author(s):
Spinner MA, Sanchez LA, Hsu AP, Shaw PA, Zerbe CS, Calvo KR, Arthur DC, Gu W, Gould CM, Brewer CC, Cowen EW, Freeman AF, Olivier KN, Uzel G, Zelazny AM, Daub JR, Spalding CD, Claypool RJ, Giri NK, Alter BP, Mace EM, Orange JS, Cuellar-Rodriguez J, Hickstein DD, Holland SM.
Name:
GATA2 deficiency: a protean disorder of haematopoiesis, lymphatics and immunity.
Author(s):
Blood.
Publication Date:
2013 November 13
DOI:
doi: 10.1182/blood-2013-07-515528
PMID:
24227816
PMCID:
PMC3916876
Author(s):
Sharfe N, Nahum A, Newell, Dadi H, Ngan B, Pereira SL, Herbrick JA, Roifman CM.
Name:
Fatal combined immunodeficiency associated with heterozygous mutation in STAT1.
Author(s):
J Allergy Clin Immunol .
Publication Date:
2013 November 13
DOI:
doi: 10.1016/j.jaci.2013.09.032.
PMID:
24239102
Author(s):
Hurst JR, Workman S, Garcha DS, Seneviratne SL, Haddock JA, Grimbacher B.
Name:
Activity, Severity and Impact of Respiratory Disease in Primary Antibody Deficiency Syndromes.
Author(s):
J Clin Immunol.
Publication Date:
2013 October 18
DOI:
doi: 10.1007/s10875-013-9942-x
PMID:
24136152
Author(s):
Platt C, Geha RS, Chou J.
Name:
Gene hunting in the genomic era: Approaches to diagnostic dilemmas in patients with primary immunodeficiencies.
Author(s):
J Allergy Clin Immunol.
Publication Date:
2013 October 4
DOI:
doi: 10.1016/j.jaci.2013.08.021.
PMID:
24100122
PMCID:
PMC3976463
Author(s):
Zhang L, Thrasher AJ, Gaspar HB.
Name:
Current progress on gene therapy for primary immunodeficiencies.
Author(s):
Gene Ther.
Publication Date:
2013 October 1
DOI:
doi: 10.1038/gt.2013.21.
PMID:
23719067
Author(s):
Milner JD, Holland SM.
Name:
The cup runneth over: lessons from the ever-expanding pool of primary immunodeficiency diseases.
Author(s):
Nat Rev Immunol.
Publication Date:
2013 September 1
DOI:
doi: 10.1038/nri3493.
PMID:
23887241
Author(s):
Orange JS.
Name:
Natural killer cell deficiency.
Author(s):
J Allergy Clin Immunol.
Publication Date:
2013 September 1
DOI:
doi: 10.1016/j.jaci.2013.07.020
PMID:
23993353
PMCID:
PMC3917661
Author(s):
Roifman CM, Seger R, Tang ML, Puck JM, Chapel H, Notarangelo LD, Casanova JL.
Name:
A phenotypic approach for IUIS PID classification and diagnosis: guidelines for clinicians at the bedside.
Author(s):
J Clin Immunol.
Publication Date:
2013 August 1
DOI:
doi: 10.1007/s10875-013-9901-6
PMID:
23657403
PMCID:
PMC4083684
Author(s):
Ives ML, Ma CS, Palendira U, Chan A, Bustamante J, Boisson-Dupuis S, Arkwright PD, Engelhard D, Averbuch D, Magdorf K, Roesler J, Peake J, Wong M, Adelstein S, Choo S, Smart JM, French MA, Fulcher DA, Cook MC, Picard C, Durandy A, Tsmura M, Kobayashi M, Uzel G, Casanova JL, Tangye SG, Deenick EK
Name:
Signal transducer and activator of transciprtion 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.
Author(s):
J Allergy Clin Immunol.
Publication Date:
2013 August 1
DOI:
doi: 10.1016/j.jaci.2013.05.029.
PMID:
23830147
PMCID:
PMC3785237
Author(s):
Kwan A, Church JA, Cowan MJ, Agarwal R, Kapoor N, Kohn DB, Lewis DB, McGhee SA, Moore TB, Stiehm ER, Porteus M, Aznar CP, Currier R, Lorey F, Puck JM.
Name:
Newborn screening for severe combined immunodeficiency and T-cell lymphopenia in California: results of the first 2 years.
Author(s):
J Allergy Clin Immunol.
Publication Date:
2013 July 1
DOI:
doi: 10.1016/j.jaci.2013.04.024
PMID:
23810098
PMCID:
PMC3759317
Author(s):
Moshous D, Martin E, Carpentier W, Lim A, Callebaut I, Canioni D, Hauck F, Majewski J, Schwartzentruber J, Nitschke P, Sirvent N, Frange P, Picard C, Blanche S, Revy P, Fischer A, Latour S, Jabado N, de Villartay JP.
Name:
Whole-exome sequencing identifies Coronin-1A deficiency in 3 siblings with immunodeficiency and EBV-associated B-cell lymphoproliferation.
Author(s):
J Allergy Clin Immunol.
Publication Date:
2013 June 1
DOI:
doi: 10.1016/j.jaci.2013.01.042.
PMID:
23522482
PMCID:
PMC3824285
Author(s):
Carneiro-Sampaio M, Moraes-Vasconcelos D, Kokron CM, Jacob CM, Toledo-Barros M, Dorna MB, Watanabe LA, Marinho AK, Castro AP, Pastorino AC, Silva CA, Ferreira MD, Rizzo LV, Kalil JE, Duarte AJ.
Name:
Primary Immunodeficiency diseases in different age groups: A report on 1,008 cases from a single Brazilian reference center.
Author(s):
J Clin Immunol.
Publication Date:
2013 May 1
DOI:
doi: 1007/s10875-013-9865-6.
PMID:
23354909
Author(s):
2Abraham RS, Recher M, Giliani S, Walter JE, Lee YN, Frugoni F, Maddox DE, Kirmani S, Notarangelo LD.
Name:
Adult-onset manifestation of idiopathic T-cell lymphopenia due to a heterozygous RAG1 mutation.
Author(s):
J Allergy Clin Immunol.
Publication Date:
2013 May 1
DOI:
doi: 10.1016/j.jaci.2012.09.016.
PMID:
23122631
Author(s):
Kotlarz D, Ziętara N, Uzel G, Weidemann T, Braun CJ, Diestelhorst J, Krawitz PM, Robinson PN, Hecht J, Puchałka J, Gertz EM, Schäffer AA, Lawrence MG, Kardava L, Pfeifer D, Baumann U, Pfister ED, Hanson EP, Schambach A, Jacobs R, Kreipe H, Moir S, Milner JD, Schwille P, Mundlos S, Klein C.
Name:
Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome.
Author(s):
J Exp Med.
Publication Date:
2013 March 13
DOI:
doi: 10.1084/jem.20111229.
PMID:
23440042
PMCID:
PMC3600901
Author(s):
Puck JM
Name:
Laboratory technology for population-based screening for severe combined immunodeficiency in neonates: the winner is T-cell receptor excision circles.
Author(s):
J Allergy Clin Immunol
Publication Date:
2012 March 1
DOI:
doi: 10.1016/j.jaci.2012.01.032.
PMID:
22285280
PMCID:
PMC3294074
Author(s):
Somech R.
Name:
T-cell receptor excision circles in primary immunodeficiencies and other T-cell immune disorders.
Author(s):
Curr Opin Allergy Clin Immunol.
Publication Date:
2011 December 11
DOI:
doi: 10.1097/ACI.0b013e32834c233a.
PMID:
21971333
Author(s):
Routes JM, Grossman WJ, Verbsky J, Laessig RH, Hoffman GL, Brokopp CD, Baker MW.
Name:
Statewide newborn screening for severe T-cell lymphopenia.
Author(s):
JAMA.
Publication Date:
2009 December 9
DOI:
doi: 10.1001/jama.2009.1806
PMID:
19996402
Shhh…tip-toe this way so I can share our educational materials with you! No need to search the aisles for desired reading.
  • Shhh…tip-toe this way so I can share our educational materials with you! No need to search the aisles for desired reading.
  • I’ve already taken the most important materials off the shelves! In fact, I've already checked out a copy of the 10 Warning Signs and Immune System Poster
  • to learn about your body’s defense system. I probably should have asked which language you prefer, since they are published in many languages.
  • I’m not only the Mayor, but also the librarian. If you need help, just ask! Until then, I’ll see you around the Village.