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Specific Defect Research Program

The goal of the Specific Defect program is to support research that studies the mechanisms and presentation of specific defects of the immune system to gain a better understanding of the defects and their impact on overall health outcomes. Our expansive database includes over 265,000 patients with various genotypes around the world, which provides an excellent platform for international collaboration. Investigators working in partnership with JMF will have access to this international database to contact other sites and coordinate joint studies.

Award Information

The Jeffrey Modell Foundation encourages novel investigations. Awards are granted quarterly throughout the year. Each award amounts up to $50,000 over a two-year project period, with a maximum of $25,000 per year. Total funds will only support direct costs and cannot be used for institutional overhead.

Required Application Materials

  1. Application: To participate, your application must be submitted through Proposal Central. Access the Proposal Central application here.
  2. Research Proposal: Please attach a detailed research proposal outlining the specific aims, background, purpose, and goals of the intended project. This proposal should be approximately 3-4 pages. Tables, figures, and graphs, etc. may also be included as supplemental documentation to support the proposal.
  3. Curriculum Vitae/Biosketch: Please attach your current curriculum vitae or biosketch, highlighting experience as it relates to your proposed project. Please list publications in order of relevance to the proposal. Please try to limit your CV/biosketch to under 5 pages.

Application Submission and Inquiries

Applications for this program are reviewed on a quarterly basis, but you may apply at any time. Applications collected throughout each quarter will be reviewed during the first month of the following quarter.

Applicants who prefer to submit a paper-based application may send all materials to the following address or by fax:

Jeffrey Modell Foundation
780 Third Avenue, 47th Floor
New York, NY 10017
Fax: 212-764-4180

All inquiries and logistical questions should be submitted to the Jeffrey Modell Foundation's Scientific Director at research@jmfworld.org.

  • Translational Research Grant
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In 2025, The Jeffrey Modell Foundation received the highest four-star rating from Charity Navigator for the 10th consecutive year, ranking #1 in Immunology out of 10,000 organizations evaluated worldwide.

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